FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury

Idiopathic pulmonary fibrosis is a common form of interstitial lung disease resulting in alveolar remodeling and progressive loss of pulmonary function because of chronic alveolar injury and failure to regenerate the respiratory epithelium. Histologically, fibrotic lesions and honeycomb structures e...

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Pubblicato in:Stem Cell Reports
Autori principali: Yuan, Tingting, Volckaert, Thomas, Redente, Elizabeth F., Hopkins, Seantel, Klinkhammer, Kylie, Wasnick, Roxana, Chao, Cho-Ming, Yuan, Jie, Zhang, Jin-San, Yao, Changfu, Majka, Susan, Stripp, Barry R., Günther, Andreas, Riches, David W.H., Bellusci, Saverio, Thannickal, Victor J., De Langhe, Stijn P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524168/
https://ncbi.nlm.nih.gov/pubmed/31056475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.003
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