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Bound Compound, Interfacial Water, and Phenyl Ring Rotation Dynamics of a Compound in the DNA Minor Groove
DB2277, a heterocyclic diamidine, is a successful design for mixed base pair (bp) DNA sequence recognition. The compound has a central aza-benzimidazole group that forms two H-bonds with a GC bp that has flanking AT bps. The NMR structure of the DB2277-DNA complex with an AAGATA recognition site seq...
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| Publicado no: | Biochemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360943/ https://ncbi.nlm.nih.gov/pubmed/30048590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00647 |
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