An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells

The aberrant activities of transcription factors such as the androgen receptor (AR) underpin prostate cancer development. While the AR cis-regulation has been extensively studied in prostate cancer, information pertaining to the spatial architecture of the AR transcriptional circuitry remains limite...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Zhang, Zhizhuo, Chng, Kern Rei, Lingadahalli, Shreyas, Chen, Zikai, Liu, Mei Hui, Do, Huy Hoang, Cai, Shaojiang, Rinaldi, Nicola, Poh, Huay Mei, Li, Guoliang, Sung, Ying Ying, Heng, Charlie L., Core, Leighton J., Tan, Si Kee, Ruan, Xiaoan, Lis, John T., Kellis, Manolis, Ruan, Yijun, Sung, Wing-Kin, Cheung, Edwin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360806/
https://ncbi.nlm.nih.gov/pubmed/30606742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.230243.117
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