PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27(Kip1) axis

BACKGROUND: Altered glucose metabolism endows tumor cells with metabolic flexibility for biosynthesis requirements. Phosphoenolpyruvate carboxykinase 1 (PCK1), a key enzyme in the gluconeogenesis pathway, is downregulated in hepatocellular carcinoma (HCC) and predicts poor prognosis. Overexpression...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: Tuo, Lin, Xiang, Jin, Pan, Xuanming, Hu, Jieli, Tang, Hua, Liang, Li, Xia, Jie, Hu, Yuan, Zhang, Wenlu, Huang, Ailong, Wang, Kai, Tang, Ni
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360696/
https://ncbi.nlm.nih.gov/pubmed/30717766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1029-y
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars