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TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways

Tumor specific Th9 cells are potential effector cells for adoptive therapy of human cancers. TNF family members OX40L, TL1A and GITRL have been shown to promote the induction of Th9 cells and antitumor immunity. However, the role of TNF-α, the prototype of the TNF superfamily cytokines, in Th9 cell...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Main Authors: Jiang, Yuxue, Chen, Jintong, Bi, Enguang, Zhao, Yinghua, Qin, Tianxue, Wang, Yiming, Wang, Alison, Gao, Sujun, Yi, Qing, Wang, Siqing
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360681/
https://ncbi.nlm.nih.gov/pubmed/30717817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0494-8
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