Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

BACKGROUND: Differentiation of induced pluripotent stem cells (iPSCs) toward hematopoietic progenitor cells (HPCs) raises high hopes for disease modeling, drug screening, and cellular therapy. Various differentiation protocols have been established to generate iPSC-derived HPCs (iHPCs) that resemble...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Cypris, Olivia, Frobel, Joana, Rai, Shivam, Franzen, Julia, Sontag, Stephanie, Goetzke, Roman, Szymanski de Toledo, Marcelo A., Zenke, Martin, Wagner, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360658/
https://ncbi.nlm.nih.gov/pubmed/30717806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0617-1
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