Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

BACKGROUND: Differentiation of induced pluripotent stem cells (iPSCs) toward hematopoietic progenitor cells (HPCs) raises high hopes for disease modeling, drug screening, and cellular therapy. Various differentiation protocols have been established to generate iPSC-derived HPCs (iHPCs) that resemble...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Cypris, Olivia, Frobel, Joana, Rai, Shivam, Franzen, Julia, Sontag, Stephanie, Goetzke, Roman, Szymanski de Toledo, Marcelo A., Zenke, Martin, Wagner, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360658/
https://ncbi.nlm.nih.gov/pubmed/30717806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0617-1
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