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Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice

BACKGROUND: Transplantation of human hematopoietic stem cells into immunodeficient mice provides a powerful in vivo model system to gain functional insights into hematopoietic differentiation. So far, it remains unclear if epigenetic changes of normal human hematopoiesis are recapitulated upon engra...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Frobel, Joana, Rahmig, Susann, Franzen, Julia, Waskow, Claudia, Wagner, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964682/
https://ncbi.nlm.nih.gov/pubmed/29796118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0499-7
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