Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice

Our preliminary data showed that VEGFR2 upregulation promoted renal ROS overproduction in high-fat diet- (HFD-) treated mice. Given that ROS-induced NLRP3 activation plays a central role in the pathogenesis of type 2 diabetic kidney injury, we evaluate whether VEGFR2 upregulation induces type 2 diab...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Zheng, Gui-Hong, Shan, Qun, Mu, Jing-Jing, Wang, Yong-Jian, Zhang, Zi-Feng, Fan, Shao-Hua, Hu, Bin, Li, Meng-Qiu, Xie, Jun, Chen, Ping, Wu, Dong-Mei, Lu, Jun, Zheng, Yuan-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360596/
https://ncbi.nlm.nih.gov/pubmed/30805082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5189819
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