Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

The peritoneal fluid of ovarian carcinoma patients promotes cancer cell invasion and metastatic spread with lysophosphatidic acid (LPA) as a potentially crucial mediator. However, the origin of LPA in ascites and the clinical relevance of individual LPA species have not been addressed. Here, we show...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Reinartz, Silke, Lieber, Sonja, Pesek, Jelena, Brandt, Dominique T., Asafova, Alina, Finkernagel, Florian, Watzer, Bernard, Nockher, Wolfgang Andreas, Nist, Andrea, Stiewe, Thorsten, Jansen, Julia M., Wagner, Uwe, Konzer, Anne, Graumann, Johannes, Grosse, Robert, Worzfeld, Thomas, Müller‐Brüsselbach, Sabine, Müller, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360368/
https://ncbi.nlm.nih.gov/pubmed/30353652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12396
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