Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

The peritoneal fluid of ovarian carcinoma patients promotes cancer cell invasion and metastatic spread with lysophosphatidic acid (LPA) as a potentially crucial mediator. However, the origin of LPA in ascites and the clinical relevance of individual LPA species have not been addressed. Here, we show...

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Udgivet i:Mol Oncol
Main Authors: Reinartz, Silke, Lieber, Sonja, Pesek, Jelena, Brandt, Dominique T., Asafova, Alina, Finkernagel, Florian, Watzer, Bernard, Nockher, Wolfgang Andreas, Nist, Andrea, Stiewe, Thorsten, Jansen, Julia M., Wagner, Uwe, Konzer, Anne, Graumann, Johannes, Grosse, Robert, Worzfeld, Thomas, Müller‐Brüsselbach, Sabine, Müller, Rolf
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360368/
https://ncbi.nlm.nih.gov/pubmed/30353652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12396
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