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Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer

Tumor cells often encounter hypoglycemic microenvironment due to rapid cell expansion. It remains elusive how tumors reprogram the genome to survive the metabolic stress. The tumor suppressor TIP60 functions as the catalytic subunit of the human NuA4 histone acetyltransferase (HAT) multi-subunit com...

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Detaylı Bibliyografya
Yayımlandı:Exp Cell Res
Asıl Yazarlar: Fang, Xiao, Lu, Guojun, Ha, Kyungsoo, Lin, Han, Du, Ye, Zuo, Qiuhong, Fu, Yi, Zou, Chaoxia, Zhang, Pumin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360337/
https://ncbi.nlm.nih.gov/pubmed/29174981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2017.11.028
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