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Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer
Tumor cells often encounter hypoglycemic microenvironment due to rapid cell expansion. It remains elusive how tumors reprogram the genome to survive the metabolic stress. The tumor suppressor TIP60 functions as the catalytic subunit of the human NuA4 histone acetyltransferase (HAT) multi-subunit com...
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Yayımlandı: | Exp Cell Res |
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Asıl Yazarlar: | , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2017
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360337/ https://ncbi.nlm.nih.gov/pubmed/29174981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2017.11.028 |
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