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Nascent DNA methylome mapping reveals inheritance of hemimethylation at CTCF/cohesin sites

The faithful inheritance of the epigenome is critical for cells to maintain gene expression programs and cellular identity across cell divisions. We mapped strand-specific DNA methylation after replication forks, and show maintenance of the vast majority of the DNA methylome and inheritance of some...

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Dades bibliogràfiques
Publicat a:Science
Autors principals: Xu, Chenhuan, Corces, Victor G.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359960/
https://ncbi.nlm.nih.gov/pubmed/29590048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan5480
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