Programming and inheritance of parental DNA methylomes in mammals

The reprogramming of parental methylomes is essential for embryonic development. In mammals, paternal 5-methylcytosines (5mCs) have been proposed to be actively converted to oxidized bases. These paternal oxidized bases and maternal 5mCs are believed to be passively diluted by cell divisions. By gen...

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Hauptverfasser: Wang, Lu, Zhang, Jun, Duan, Jialei, Gao, Xinxing, Zhu, Wei, Lu, Xingyu, Yang, Lu, Zhang, Jing, Li, Guoqiang, Ci, Weimin, Li, Wei, Zhou, Qi, Aluru, Neel, Tang, Fuchou, He, Chuan, Huang, Xingxu, Liu, Jiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096154/
https://ncbi.nlm.nih.gov/pubmed/24813617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.017
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