Sperm, but Not Oocyte, DNA Methylome Is Inherited by Zebrafish Early Embryos

5-methylcytosine is a major epigenetic modification that is sometimes called “the fifth nucleotide.” However, our knowledge of how offspring inherit the DNA methylome from parents is limited. We generated nine single-base resolution DNA methylomes, including zebrafish gametes and early embryos. The...

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Huvudupphovsmän: Jiang, Lan, Zhang, Jing, Wang, Jing-Jing, Wang, Lu, Zhang, Li, Li, Guoqiang, Yang, Xiaodan, Ma, Xin, Sun, Xin, Cai, Jun, Zhang, Jun, Huang, Xingxu, Yu, Miao, Wang, Xuegeng, Liu, Feng, Wu, Chung-I, He, Chuan, Zhang, Bo, Ci, Weimin, Liu, Jiang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081501/
https://ncbi.nlm.nih.gov/pubmed/23663777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.041
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