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Mosaic Y loss is moderately associated with solid tumor risk

Mosaic loss of the Y chromosome (mLOY) in peripheral leukocytes is a somatic event in which a fraction of leukocytes have lost the entire Y chromosome. The frequency of mLOY increases with age and may reflect poor genomic maintenance as well as clonal imbalances in normal immune function, making mLO...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Loftfield, Erikka, Zhou, Weiyin, Yeager, Meredith, Chanock, Stephen J., Freedman, Neal D., Machiela, Mitchell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359954/
https://ncbi.nlm.nih.gov/pubmed/30510122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2566
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