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Analysis of Glipizide Binding to Normal and Glycated Human Serum Albumin by High-Performance Affinity Chromatography
In diabetes, the elevated levels of glucose in the blood stream can result in the non-enzymatic glycation of proteins such as human serum albumin (HSA). This type of modification has been shown to affect the interactions of some drugs with HSA, including several sulfonylurea drugs that are used to t...
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| Veröffentlicht in: | Anal Bioanal Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6359935/ https://ncbi.nlm.nih.gov/pubmed/25912461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8688-0 |
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