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Selective autophagy as a potential therapeutic target for neurodegenerative disorders

Cells rely on surveillance systems such as autophagy to handle protein alterations and organelle damage. Dysfunctional autophagy, an evolutionarily conserved cellular mechanism for degradation of intracellular components in lysosomes, frequently leads to neurodegeneration. The neuroprotective effect...

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Detalles Bibliográficos
Publicado en:Lancet Neurol
Main Authors: Scrivo, Aurora, Bourdenx, Mathieu, Pampliega, Olatz, Cuervo, Ana Maria
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359907/
https://ncbi.nlm.nih.gov/pubmed/30129476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(18)30238-2
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