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Selective autophagy as a potential therapeutic target for neurodegenerative disorders
Cells rely on surveillance systems such as autophagy to handle protein alterations and organelle damage. Dysfunctional autophagy, an evolutionarily conserved cellular mechanism for degradation of intracellular components in lysosomes, frequently leads to neurodegeneration. The neuroprotective effect...
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| Pubblicato in: | Lancet Neurol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6359907/ https://ncbi.nlm.nih.gov/pubmed/30129476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(18)30238-2 |
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