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Synthesis, In Vitro Screening and Docking Studies of New Thiosemicarbazide Derivatives as Antitubercular Agents

A series of thiosemicarbazide derivatives was designed and synthesized by reaction of carboxylic acid hydrazide with isothiocyanates. The molecular structures of the investigated thiosemicarbazides were confirmed and characterized by spectroscopic analysis. The conformational preference of carbonylt...

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Pitucha, Monika, Karczmarzyk, Zbigniew, Swatko-Ossor, Marta, Wysocki, Waldemar, Wos, Maciej, Chudzik, Kamil, Ginalska, Grazyna, Fruzinski, Andrzej
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359303/
https://ncbi.nlm.nih.gov/pubmed/30641902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24020251
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