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Fumaric Acids Directly Influence Gene Expression of Neuroprotective Factors in Rodent Microglia

Dimethylfumarate (DMF) has been approved the for treatment of relapsing-remitting multiple sclerosis. The mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood, notably for brain resident cells. Therefore we investigated potential dire...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kronenberg, Jessica, Pars, Kaweh, Brieskorn, Marina, Prajeeth, Chittappen K., Heckers, Sandra, Schwenkenbecher, Philipp, Skripuletz, Thomas, Pul, Refik, Pavlou, Andreas, Stangel, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358967/
https://ncbi.nlm.nih.gov/pubmed/30650518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020325
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