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RUNX1-ETO: Attacking the Epigenome for Genomic Instable Leukemia
Oncogenic fusion protein RUNX1-ETO is the product of the t(8;21) translocation, responsible for the most common cytogenetic subtype of acute myeloid leukemia. RUNX1, a critical transcription factor in hematopoietic development, is fused with almost the entire ETO sequence with the ability to recruit...
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| 出版年: | Int J Mol Sci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6358732/ https://ncbi.nlm.nih.gov/pubmed/30654457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020350 |
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