Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope

Zika virus (ZIKV) is a major human pathogen and member of the Flavivirus genus in the Flaviviridae family. In contrast to most other insect-transmitted flaviviruses, ZIKV also can be transmitted sexually and from mother to fetus in humans. During recent outbreaks, ZIKV infections have been linked to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Long, Feng, Doyle, Michael, Fernandez, Estefania, Miller, Andrew S., Klose, Thomas, Sevvana, Madhumati, Bryan, Aubrey, Davidson, Edgar, Doranz, Benjamin J., Kuhn, Richard J., Diamond, Michael S., Crowe, James E., Rossmann, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358714/
https://ncbi.nlm.nih.gov/pubmed/30642974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815432116
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