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Risk gene-set and pathways in 22q11.2 deletion-related schizophrenia: a genealogical molecular approach

The 22q11.2 deletion is a strong, but insufficient, “first hit” genetic risk factor for schizophrenia (SZ). We attempted to identify “second hits” from the entire genome in a unique multiplex 22q11.2 deletion syndrome (DS) family. Bioinformatic analysis of whole-exome sequencing and comparative-geno...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Michaelovsky, Elena, Carmel, Miri, Frisch, Amos, Salmon-Divon, Mali, Pasmanik-Chor, Metsada, Weizman, Abraham, Gothelf, Doron
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358611/
https://ncbi.nlm.nih.gov/pubmed/30710087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0354-9
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