Biological Effects of COMT Haplotypes and Psychosis Risk in 22q11.2 Deletion Syndrome

BACKGROUND: 22q11.2 deletion syndrome (22q11.2DS) is the most common genetic syndrome associated with schizophrenia. The catechol-o-methyltransferase (COMT) gene is located in the obligatory deletion region, and possible associations between COMT variants and neuropsychiatric manifestations in 22q11...

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Main Authors: Gothelf, Doron, Law, Amanda J., Frisch, Amos, Chen, Jingshan, Zarchi, Omer, Michaelovsky, Elena, Ren-Patterson, Renee, Lipska, Barbara K., Carmel, Miri, Kolachana, Bhaskar, Weizman, Abraham, Weinberger, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872263/
https://ncbi.nlm.nih.gov/pubmed/23992923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.07.021
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