Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease

OBJECTIVE: Congenital heart disease (CHD) is the most frequent birth defect worldwide. The number of adult patients with CHD, now referred to as ACHD, is increasing with improved surgical and treatment interventions. However the mechanisms whereby ACHD predisposes patients to heart dysfunction are s...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Wilmanns, Julia C., Pandey, Raghav, Hon, Olivia, Chandran, Anjana, Schilling, Jan M., Forte, Elvira, Wu, Qizhu, Cagnone, Gael, Bais, Preeti, Philip, Vivek, Coleman, David, Kocalis, Heidi, Archer, Stuart K., Pearson, James T., Ramialison, Mirana, Heineke, Joerg, Patel, Hemal H., Rosenthal, Nadia A., Furtado, Milena B., Costa, Mauro W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358551/
https://ncbi.nlm.nih.gov/pubmed/30482476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.11.002
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