Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing

OBJECTIVE: Hypothalamic glucose sensing (HGS) initiates insulin secretion (IS) via a vagal control, participating in energy homeostasis. This requires mitochondrial reactive oxygen species (mROS) signaling, dependent on mitochondrial fission, as shown by invalidation of the hypothalamic DRP1 protein...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Desmoulins, Lucie, Chrétien, Chloé, Paccoud, Romain, Collins, Stephan, Cruciani-Guglielmacci, Céline, Galinier, Anne, Liénard, Fabienne, Quinault, Aurore, Grall, Sylvie, Allard, Camille, Fenech, Claire, Carneiro, Lionel, Mouillot, Thomas, Fournel, Audren, Knauf, Claude, Magnan, Christophe, Fioramonti, Xavier, Pénicaud, Luc, Leloup, Corinne
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358535/
https://ncbi.nlm.nih.gov/pubmed/30553770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.11.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados