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Mitochondrial polymorphisms contribute to aging phenotypes in MNX mouse models
Many inbred strains of mice develop spontaneous tumors as they age. Recent awareness of the impacts of mitochondrial DNA (mtDNA) on cancer and aging have inspired developing a Mitochondrial-Nuclear Exchange (MNX) mouse model in which nuclear DNA is paired with mitochondrial genomes from other strain...
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| Udgivet i: | Cancer Metastasis Rev |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6358467/ https://ncbi.nlm.nih.gov/pubmed/30547266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-018-9773-6 |
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