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Multiple roles of the non-structural protein 3 (nsP3) alphavirus unique domain (AUD) during Chikungunya virus genome replication and transcription

Chikungunya virus (CHIKV) is a re-emerging Alphavirus causing fever, joint pain, skin rash, arthralgia, and occasionally death. Antiviral therapies and/or effective vaccines are urgently required. CHIKV biology is poorly understood, in particular the functions of the non-structural protein 3 (nsP3)....

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Gao, Yanni, Goonawardane, Niluka, Ward, Joseph, Tuplin, Andrew, Harris, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358111/
https://ncbi.nlm.nih.gov/pubmed/30668592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007239
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