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Transition from a meiotic to a somatic-like DNA damage response during the pachytene stage in mouse meiosis

Homologous recombination (HR) is the principal mechanism of DNA repair acting during meiosis and is fundamental for the segregation of chromosomes and the increase of genetic diversity. Nevertheless, non-homologous end joining (NHEJ) mechanisms can also act during meiosis, mainly in response to exog...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Enguita-Marruedo, Andrea, Martín-Ruiz, Marta, García, Eva, Gil-Fernández, Ana, Parra, María Teresa, Viera, Alberto, Rufas, Julio S., Page, Jesús
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358097/
https://ncbi.nlm.nih.gov/pubmed/30668564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007439
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