Transition from a meiotic to a somatic-like DNA damage response during the pachytene stage in mouse meiosis

Homologous recombination (HR) is the principal mechanism of DNA repair acting during meiosis and is fundamental for the segregation of chromosomes and the increase of genetic diversity. Nevertheless, non-homologous end joining (NHEJ) mechanisms can also act during meiosis, mainly in response to exog...

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Vydáno v:PLoS Genet
Hlavní autoři: Enguita-Marruedo, Andrea, Martín-Ruiz, Marta, García, Eva, Gil-Fernández, Ana, Parra, María Teresa, Viera, Alberto, Rufas, Julio S., Page, Jesús
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358097/
https://ncbi.nlm.nih.gov/pubmed/30668564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007439
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