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Non-ion channel therapeutics for heart failure and atrial fibrillation: are CaMKII inhibitors ready for clinical use?
The Ca(2+)-calmodulin dependent protein kinase II (CaMKII) is an established central mediator of electrophysiological and contractile responses to cardiac stress, and its hyper-activation in cardiac diseases has been linked to heart failure (HF) and atrial and ventricular arrhythmias. Here we summar...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6358017/ https://ncbi.nlm.nih.gov/pubmed/29079077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.10.010 |
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