Analyzing Vaccine Trials in Epidemics With Mild and Asymptomatic Infection

Vaccine efficacy against susceptibility to infection (VE(S)), regardless of symptoms, is an important endpoint of vaccine trials for pathogens with a high proportion of asymptomatic infection, because such infections may contribute to onward transmission and long-term sequelae, such as congenital Zi...

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Udgivet i:Am J Epidemiol
Main Authors: Kahn, Rebecca, Hitchings, Matt, Wang, Rui, Bellan, Steven E, Lipsitch, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Practice of Epidemiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357804/
https://ncbi.nlm.nih.gov/pubmed/30329134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwy239
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