The CCR2(+) Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) typically arises in fibrotic or cirrhotic livers, which are characterized by pathogenic angiogenesis. Myeloid immune cells, specifically tumor-associated macrophages (TAMs), may represent potential novel therapeutic targets in HCC, complementing...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Bartneck, Matthias, Schrammen, Peter L., Möckel, Diana, Govaere, Olivier, Liepelt, Anke, Krenkel, Oliver, Ergen, Can, McCain, Misti Vanette, Eulberg, Dirk, Luedde, Tom, Trautwein, Christian, Kiessling, Fabian, Reeves, Helen, Lammers, Twan, Tacke, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357791/
https://ncbi.nlm.nih.gov/pubmed/30704985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.10.007
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