Inhibition of HBV Transcription From cccDNA With Nitazoxanide by Targeting the HBx–DDB1 Interaction

BACKGROUND & AIMS: Hepatitis B virus (HBV) infection is a major health concern worldwide. Although currently used nucleos(t)ide analogs efficiently inhibit viral replication, viral proteins transcribed from the episomal viral covalently closed circular DNA (cccDNA) minichromosome continue to be...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Mol Gastroenterol Hepatol
Egile Nagusiak: Sekiba, Kazuma, Otsuka, Motoyuki, Ohno, Motoko, Yamagami, Mari, Kishikawa, Takahiro, Suzuki, Tatsunori, Ishibashi, Rei, Seimiya, Takahiro, Tanaka, Eri, Koike, Kazuhiko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357790/
https://ncbi.nlm.nih.gov/pubmed/30704981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.10.010
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