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ISGF3 with reduced phosphorylation is associated with constitutive expression of interferon-induced genes in aging cells
During cellular aging, many changes in cellular functions occur. A hallmark of aged cells is secretion of inflammatory mediators, which collectively is referred to as the senescence-associated secretory phenotype (SASP). However, the mechanisms underlying such changes are unclear. Canonically, the e...
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| Publicado no: | NPJ Aging Mech Dis |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237867/ https://ncbi.nlm.nih.gov/pubmed/30455980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-018-0030-6 |
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