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Myeloid Derived Suppressor Cells Inhibit Natural Killer Cells in Patients with Hepatocellular Carcinoma via the NKp30 Receptor

Several immune suppressive mechanisms that evade the host immune response have been described in patients with hepatocellular carcinoma (HCC); one of these mechanisms is expansion of myeloid-derived suppressor cells (MDSCs). MDSCs have been shown to inhibit T cell responses in tumor-bearing mice, bu...

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Publicado en:Hepatology
Autores principales: Hoechst, Bastian, Voigtlaender, Torsten, Ormandy, Lars, Gamrekelashvili, Jaba, Zhao, Fei, Wedemeyer, Heiner, Lehner, Frank, Manns, Michael P., Greten, Tim F., Korangy, Firouzeh
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357774/
https://ncbi.nlm.nih.gov/pubmed/19551844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23054
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