Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal Epithelium

BACKGROUND & AIMS: Hypoxia-associated pathways influence the development of inflammatory bowel disease. Adaptive responses to hypoxia are mediated through hypoxia-inducible factors, which are regulated by iron-dependent hydroxylases. Signals reflecting oxygen tension and iron levels in enterocyt...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Simmen, Simona, Cosin-Roger, Jesus, Melhem, Hassan, Maliachovas, Nikolaos, Maane, Max, Baebler, Katharina, Weder, Bruce, Maeyashiki, Chiaki, Spanaus, Katharina, Scharl, Michael, de Vallière, Cheryl, Zeitz, Jonas, Vavricka, Stephan R., Hausmann, Martin, Rogler, Gerhard, Ruiz, Pedro A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357696/
https://ncbi.nlm.nih.gov/pubmed/30704983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.10.006
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