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Postconditioning with inhaled hydrogen attenuates skin ischemia/reperfusion injury through the RIP-MLKL-PGAM5/Drp1 necrotic pathway

This study explored the flap-protective effects of high concentrations of hydrogen (HCH) inhalation in a rat flap ischemia/reperfusion (I/R) injury model and the potential mechanism of necroptosis. Forty-five male Sprague-Dawley rats were randomly divided into three groups: SH, IR and HCH groups. Af...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Dong, Xin-Hang, Liu, Hao, Zhang, Ming-Zi, Zhao, Peng-Xiang, Liu, Shu, Hao, Yan, Wang, You-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357323/
https://ncbi.nlm.nih.gov/pubmed/30788005
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