Diabetes impairs the protective effects of sevoflurane postconditioning in the myocardium subjected to ischemia/ reperfusion injury in rats: important role of Drp1

BACKGROUND: Sevoflurane postconditioning (SevP) effectively relieves myocardial ischemia/reperfusion (I/R) injury but performs poorly in the diabetic myocardium. Previous studies have revealed the important role of increased oxidative stress in diabetic tissues. Notably, mitochondrial fission mediat...

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Vydáno v:BMC Cardiovasc Disord
Hlavní autoři: Yu, Jing, He, Jiandong, Yang, Wenqu, Wang, Xiang, Shi, Gaoxiang, Duan, Yinglei, Wang, Hui, Han, Chongfang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885510/
https://ncbi.nlm.nih.gov/pubmed/33593294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-021-01906-w
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