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Platinum Resistance in Ovarian Cancer: Role of DNA Repair

Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. It is initially responsive to cisplatin and carboplatin, two DNA damaging agents used in first line therapy. However, almost invariably, patients relapse with a tumor resistant to subsequent treatment with platinum containing d...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Damia, Giovanna, Broggini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357127/
https://ncbi.nlm.nih.gov/pubmed/30669514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010119
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