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Combination of paclitaxel, bevacizumab and MEK162 in second line treatment in platinum-relapsing patient derived ovarian cancer xenografts

Advanced ovarian cancer is very responsive to first line platinum therapy, however almost invariably it relapses with a resistant disease. We have reported that patient derived ovarian xenografts (PDXs), independently from the degree of the initial response to cisplatin (DDP), show a significantly l...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Ricci, Francesca, Guffanti, Federica, Damia, Giovanna, Broggini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450309/
https://ncbi.nlm.nih.gov/pubmed/28558767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0662-3
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