Altered VEGF Splicing Isoform Balance in Tumor Endothelium Involves Activation of Splicing Factors Srpk1 and Srsf1 by the Wilms’ Tumor Suppressor Wt1

Angiogenesis is one hallmark of cancer. Vascular endothelial growth factor (VEGF) is a known inducer of angiogenesis. Many patients benefit from antiangiogenic therapies, which however have limitations. Although VEGF is overexpressed in most tumors, different VEGF isoforms with distinct angiogenic p...

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Publicado en:Cells
Main Authors: Wagner, Kay-Dietrich, El Maï, Mounir, Ladomery, Michael, Belali, Tareg, Leccia, Nathalie, Michiels, Jean-François, Wagner, Nicole
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356959/
https://ncbi.nlm.nih.gov/pubmed/30641926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010041
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