Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms

The recombinant antibody fragments generated against the toxic components of scorpion venoms are considered a promising alternative for obtaining new antivenoms for therapy. Using directed evolution and site-directed mutagenesis, it was possible to generate a human single-chain antibody fragment wit...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Riaño-Umbarila, Lidia, Gómez-Ramírez, Ilse V., Ledezma-Candanoza, Luis M., Olamendi-Portugal, Timoteo, Rodríguez-Rodríguez, Everardo Remi, Fernández-Taboada, Guillermo, Possani, Lourival D., Becerril, Baltazar
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356842/
https://ncbi.nlm.nih.gov/pubmed/30634620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11010032
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