Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells

Pannexin 1 (PANX1) is a channel-forming glycoprotein expressed in many tissues including the skin. PANX1 channels allow the passage of ions and molecules up to 1 kDa, including ATP and other metabolites. In this study, we show that PANX1 is highly expressed in human melanoma tumors at all stages of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Freeman, Taylor J., Sayedyahossein, Samar, Johnston, Danielle, Sanchez-Pupo, Rafael E., O’Donnell, Brooke, Huang, Kenneth, Lakhani, Zameena, Nouri-Nejad, Daniel, Barr, Kevin J., Harland, Luke, Latosinsky, Steven, Grant, Aaron, Dagnino, Lina, Penuela, Silvia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356688/
https://ncbi.nlm.nih.gov/pubmed/30654593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010102
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