Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation

Pannexin 1 (Panx1) is a channel-forming glycoprotein important in paracrine signaling and cellular development. In this study, we discovered that mice globally lacking Panx1 (KO) have significantly greater total fat mass and reduced lean mass compared to wild type (WT) mice under a normal diet. Desp...

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Publicado no:Sci Rep
Main Authors: Lee, Vanessa R., Barr, Kevin J., Kelly, John J., Johnston, Danielle, Brown, Cody F. C., Robb, Kevin P., Sayedyahossein, Samar, Huang, Kenneth, Gros, Robert, Flynn, Lauren E., Penuela, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212408/
https://ncbi.nlm.nih.gov/pubmed/30385873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34234-9
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