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Differential Mechanisms of Cell Death Induced by HDAC Inhibitor SAHA and MDM2 Inhibitor RG7388 in MCF-7 Cells

Gene expression is often altered by epigenetic modifications that can significantly influence the growth ability and progression of cancers. SAHA (Suberoylanilide hydroxamic acid, also known as Vorinostat), a well-known Histone deacetylase (HDAC) inhibitor, can stop cancer growth and metastatic proc...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Natarajan, Umamaheswari, Venkatesan, Thiagarajan, Radhakrishnan, Vijayaraghavan, Samuel, Shila, Rathinavelu, Appu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356663/
https://ncbi.nlm.nih.gov/pubmed/30583560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010008
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