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The Capacity of Long-Term In Vitro Proliferation of Acute Myeloid Leukemia Cells Supported Only by Exogenous Cytokines Is Associated with a Patient Subset with Adverse Outcome

Acute myeloid leukemia (AML) is an aggressive malignancy, which is highly heterogeneous with regard to chemosensitivity and biological features. The AML cell population is organized in a hierarchy that is reflected in the in vitro growth characteristics, with only a minority of cells being able to p...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Brenner, Annette K., Aasebø, Elise, Hernandez-Valladares, Maria, Selheim, Frode, Berven, Frode, Grønningsæter, Ida-Sofie, Bartaula-Brevik, Sushma, Bruserud, Øystein
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356272/
https://ncbi.nlm.nih.gov/pubmed/30634713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010073
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