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Altered hypoxia‐inducible factor–1α (HIF‐1α) signaling contributes to impaired angiogenesis in fetal lambs with persistent pulmonary hypertension of the newborn (PPHN)

Previous studies in adult pulmonary hypertension reported that increased hypoxia‐inducible factor–1α (HIF‐1α) signaling contributes to pulmonary vascular remodeling. However, alterations in endothelial HIF‐1α signaling and its contribution to impaired angiogenesis in persistent pulmonary hypertensio...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Makker, Kartikeya, Afolayan, Adeleye J., Teng, Ru‐Jeng, Konduri, Girija G.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355993/
https://ncbi.nlm.nih.gov/pubmed/30706701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13986
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