Critical role of OX40 signaling in the TCR-independent phase of human and murine thymic Treg generation

Regulatory T cells (Tregs) play a pivotal role in immune-tolerance, and loss of Treg function can lead to the development of autoimmunity. Natural Tregs generated in the thymus substantially contribute to the Treg pool in the periphery, where they suppress self-reactive effector T cells (Teff) respo...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Mol Immunol
Päätekijät: Kumar, Prabhakaran, Marinelarena, Alejandra, Raghunathan, Divya, Ragothaman, Vandhana K, Saini, Shikha, Bhattacharya, Palash, Fan, Jilao, Epstein, Alan L, Maker, Ajay V, Prabhakar, Bellur S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355936/
https://ncbi.nlm.nih.gov/pubmed/29578532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2018.8
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