Critical role of OX40 signaling in the TCR-independent phase of human and murine thymic Treg generation

Regulatory T cells (Tregs) play a pivotal role in immune-tolerance, and loss of Treg function can lead to the development of autoimmunity. Natural Tregs generated in the thymus substantially contribute to the Treg pool in the periphery, where they suppress self-reactive effector T cells (Teff) respo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Mol Immunol
Egile Nagusiak: Kumar, Prabhakaran, Marinelarena, Alejandra, Raghunathan, Divya, Ragothaman, Vandhana K, Saini, Shikha, Bhattacharya, Palash, Fan, Jilao, Epstein, Alan L, Maker, Ajay V, Prabhakar, Bellur S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355936/
https://ncbi.nlm.nih.gov/pubmed/29578532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2018.8
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