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Critical role of OX40 signaling in the TCR-independent phase of human and murine thymic Treg generation
Regulatory T cells (Tregs) play a pivotal role in immune-tolerance, and loss of Treg function can lead to the development of autoimmunity. Natural Tregs generated in the thymus substantially contribute to the Treg pool in the periphery, where they suppress self-reactive effector T cells (Teff) respo...
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| 發表在: | Cell Mol Immunol |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355936/ https://ncbi.nlm.nih.gov/pubmed/29578532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2018.8 |
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