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Critical role of OX40 signaling in the TCR-independent phase of human and murine thymic Treg generation

Regulatory T cells (Tregs) play a pivotal role in immune-tolerance, and loss of Treg function can lead to the development of autoimmunity. Natural Tregs generated in the thymus substantially contribute to the Treg pool in the periphery, where they suppress self-reactive effector T cells (Teff) respo...

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書目詳細資料
發表在:Cell Mol Immunol
Main Authors: Kumar, Prabhakaran, Marinelarena, Alejandra, Raghunathan, Divya, Ragothaman, Vandhana K, Saini, Shikha, Bhattacharya, Palash, Fan, Jilao, Epstein, Alan L, Maker, Ajay V, Prabhakar, Bellur S
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355936/
https://ncbi.nlm.nih.gov/pubmed/29578532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2018.8
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