Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma

INTRODUCTION: Therapeutic options for diffuse malignant peritoneal mesothelioma (DMPM) are limited to surgery and locoregional chemotherapy. Despite improvements in survival rates, patients eventually succumb to disease progression. We investigated splicing deregulation both as molecular prognostic...

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Publicado en:EBioMedicine
Autores principales: Sciarrillo, Rocco, Wojtuszkiewicz, Anna, El Hassouni, Btissame, Funel, Niccola, Gandellini, Paolo, Lagerweij, Tonny, Buonamici, Silvia, Blijlevens, Maxime, Zeeuw van der Laan, Eveline A., Zaffaroni, Nadia, Deraco, Marcello, Kusamura, Shigeki, Würdinger, Tom, Peters, Godefridus J., Molthoff, Carla F.M., Jansen, Gerrit, Kaspers, Gertjan J.L., Cloos, Jacqueline, Giovannetti, Elisa
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355829/
https://ncbi.nlm.nih.gov/pubmed/30581150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.12.025
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